abstract：BACKGROUND:The proportion of live births by cesarean delivery (CD) in China is significant, with some, particularly rural, provinces reporting up to 62.5%. The No Pain Labor & Delivery-Global Health Initiative (NPLD-GHI) was established to improve obstetric and neonatal outcomes in China, including through a reduction ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Guo JC,Qi XQ,Tsen LC,Sun Y,Ouanes JP,Xia Y,Gao WD,Ruthazer R,Hu F,Hu LQ

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:District-level hospitals (DLHs) are the main providers of surgical services for rural populations in Sub-Saharan Africa (SSA). Skilled teams are essential for surgical care, and gaps in anesthesia impact negatively on surgical capacity and outcomes. This study, from a baseline of a project scaling-up access ...

journal_title：Anesthesia and analgesia

authors： Gajewski J,Pittalis C,Lavy C,Borgstein E,Bijlmakers L,Mwapasa G,Cheelo M,Le G,Juma A,Kachimba J,Marealle P,Mkandawire N,Chilonga K,Brugha R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Severe pain has been linked to depression, which raises the question of whether epidural analgesia (EDA) during childbirth is associated with a reduced risk of postpartum depression (PPD). This association has been explored previously, but the studies were restricted by small sample sizes and the inability t...

journal_title：Anesthesia and analgesia

authors： Eckerdal P,Kollia N,Karlsson L,Skoog-Svanberg A,Wikström AK,Högberg U,Skalkidou A

更新日期：2020-03-01 00:00:00

abstract：:External cephalic version is a technique that decreases the need for cesarean delivery in patients with breech presentation. Several techniques exist to increase the success of external cephalic version; however, there are no studies comparing different tocolytics in patients who also received neuraxial anesthesia. We...

journal_title：Anesthesia and analgesia

authors： Katz D,Riley K,Kim E,Beilin Y

更新日期：2020-03-01 00:00:00

abstract：:The common treatment for postoperative pain is prescription opioids. Yet, these drugs have limited effect in preventing chronic pain from surgical intervention and have in part contributed to the opioid epidemic. Recently, preemptive analgesia and multimodal analgesia have been proposed with widely gained acceptance i...

journal_title：Anesthesia and analgesia

authors： Horn A,Kaneshiro K,Tsui BCH

更新日期：2020-03-01 00:00:00

abstract：:In recent years, there have been escalating concerns related to the opioid epidemic. With a steadily increasing opioid supply, it is critical to provide proper education to patients who are prescribed these medications. Education should be emphasized as a means of ensuring safe use and potentially as a strategy for cu...

journal_title：Anesthesia and analgesia

authors： Lee BH,Wu CL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS:We performed a subgroup investigation of a prosp...

journal_title：Anesthesia and analgesia

authors： Lachmann G,Mörgeli R,Kuenz S,Piper SK,Spies C,Kurpanik M,Weber-Carstens S,Wollersheim T,BIOCOG Consortium.

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The incremental dose of opioids used in chronic pain management often leads to a reduced opioid analgesic effect, opioid misuse, and addiction. Central dopamine (DA) dysfunction contributes to the chronicity of pain and a decreased opioid analgesic effect. Methylphenidate (MPH/Ritalin) enhances central DA fu...

journal_title：Anesthesia and analgesia

authors： You Z,Ding W,Doheny JT,Shen S,Yang J,Yang L,Chen L,Zhu S,Mao J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Incomplete reversal with a recommended 5-g dose of idarucizumab has been reported in patients with excessively high dabigatran concentrations. A timely detection of reversal failure after idarucizumab using whole blood (WB) coagulation testing is clinically useful. The aims of this study were to determine re...

journal_title：Anesthesia and analgesia

authors： Takeshita S,Tanaka KA,Sawa T,Sanda M,Mizobe T,Ogawa S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Burnout is a psychological syndrome that results from chronic exposure to job stress. It is defined by a triad of emotional exhaustion, depersonalization, and reduced personal accomplishment. In research, mostly from high-income countries, burnout is common in health care professionals, especially in anesthe...

journal_title：Anesthesia and analgesia

authors： Mumbwe MC,McIsaac D,Jarman A,Bould MD

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:We previously reported that the duration of hospitalization was not different between isoflurane and sevoflurane. But more plausible consequences of using soluble volatile anesthetics are delayed emergence from anesthesia and prolonged stays in the postanesthesia care unit (PACU). We therefore compared isofl...

journal_title：Anesthesia and analgesia

authors： Maheshwari K,Ahuja S,Mascha EJ,Cummings KC 3rd,Chahar P,Elsharkawy H,Kurz A,Turan A,Sessler DI

更新日期：2020-02-01 00:00:00

abstract：:The primary outcome of this 8-year retrospective review was the failure of spinal anesthetic (SA) in elective hip and knee joint arthroplasty surgery. Of 3542 SAs, a total of 135 failures were identified (3.8%). Factors associated with increased odds of failure were younger age (odds ratio [OR], 1.03; 95% confidence i...

journal_title：Anesthesia and analgesia

authors： Colish J,Milne AD,Brousseau P,Uppal V

更新日期：2020-01-01 00:00:00

abstract：:The understanding of anesthetic side effects on the heart has been hindered by the lack of sophisticated clinical models. Using micropatterned human-induced pluripotent stem cell-derived cardiomyocytes, we obtained cardiac muscle depressant profiles for propofol, etomidate, and our newly identified anesthetic compound...

journal_title：Anesthesia and analgesia

authors： Chang ACY,Chang ACH,Nicin L,Weber GJ,Holbrook C,Davies MF,Blau HM,Bertaccini EJ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Recently, there has been significant focus on the effects of anesthesia on the developing brain. Concern is heightened in children <3 years of age requiring lengthy and/or multiple anesthetics. Hypospadias correction is common in otherwise healthy children and may require both lengthy and repeated anesthetic...

journal_title：Anesthesia and analgesia

authors： Adler AC,Chandrakantan A,Sawires Y,Lee AD,Hart M,Koh CJ,Janzen NK,Austin PF,Andropoulos DB

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

journal_title：Anesthesia and analgesia

authors： Shin HJ,Do SH,Lee JS,Kim TK,Na HS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The impact of physiological adjustments throughout pregnancy on maternal vital signs and laboratory values has yet to be fully defined. The present study was designed to determine the normal range of these parameters among healthy pregnant women during the peripartum period. METHODS:This is a retrospective ...

journal_title：Anesthesia and analgesia

authors： Gat R,Hadar E,Orbach-Zinger S,Shochat T,Kushnir S,Einav S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Lung isolation with bronchial blockers is a well-described and accepted procedure, often described for use during the management of massive hemoptysis. Recommendations for balloon inflation are sparse, with some advocating for saline whereas other suggest air, including the manufacturers. We sought to evalua...

journal_title：Anesthesia and analgesia

authors： Gilbert CR,Mallow C,Wishire CL,Chang SC,Yarmus LB,Vallieres E,Haeck K,Gorden JA

更新日期：2019-12-01 00:00:00

abstract：:Clinical practice parameters have been published with greater frequency by professional societies and groups of experts. These publications run the gamut of practice standards, practice guidelines, consensus statements or practice advisories, position statements, and practice alerts. The definitions of these terms hav...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Joshi GP,Gan TJ,Vetter TR

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to compare the characteristics of culture-positive and culture-negative status in septic patients. We also determined whether culture status is associated with mortality and whether unique variables are associated with mortality in culture-positive and culture-negative...

journal_title：Anesthesia and analgesia

authors： Sigakis MJG,Jewell E,Maile MD,Cinti SK,Bateman BT,Engoren M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Medical procedures often evoke pain and anxiety in pediatric patients. Virtual reality (VR) is a relatively new intervention that can be used to provide distraction during, or to prepare patients for, medical procedures. This meta-analysis is the first to collate evidence on the effectiveness of VR on reduci...

journal_title：Anesthesia and analgesia

authors： Eijlers R,Utens EMWJ,Staals LM,de Nijs PFA,Berghmans JM,Wijnen RMH,Hillegers MHJ,Dierckx B,Legerstee JS

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:For emergent procedures, in-house teams are required for immediate patient care. However, for many procedures, there is time to bring in a call team from home without increasing patient morbidity. Anesthesia providers taking subspecialty or backup call from home are required to return to the hospital within ...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,Diez C,Potnuru P

更新日期：2019-11-01 00:00:00

abstract：:This study evaluates the changes of oxygen saturation (SpO2) after intravenous administration of methylene blue in 103 patients undergoing open repair of thoracoabdominal aortic aneurysms. We found that SpO2 decreased by a median (interquartile range [IQR]) of 49% (37%-81%) <1 minute after methylene blue administratio...

journal_title：Anesthesia and analgesia

authors： Rong LQ,Mauer E,Mustapich TL,White RS,Di Franco A,Girardi LN,Gaudino M,Pryor KO

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Local anesthetics cause reversible block of pain and robustly inhibit TWIK-related K channel (TREK-1) currents. Before local anesthesia onset, injection of local anesthetics can cause unwanted transient pain. TREK-1 is an anesthetic-sensitive potassium channel that when inhibited produces pain. A disordered ...

journal_title：Anesthesia and analgesia

authors： Pavel MA,Chung HW,Petersen EN,Hansen SB

更新日期：2019-10-01 00:00:00

abstract：:Heart transplant recipients are susceptible to a number of complications in the immediate postoperative period. Despite advances in surgical techniques, mechanical circulatory support (MCS), and immunosuppression, evidence supporting optimal management strategies of the critically ill transplant patient is lacking on ...

journal_title：Anesthesia and analgesia

authors： Shen T,Huh MH,Czer LS,Vaidya A,Esmailian F,Kobashigawa JA,Nurok M

更新日期：2019-10-01 00:00:00

abstract：:Effective communication is essential in today's health care environment, and poor communication can lead to conflict among health care providers. Differences in cultures and beliefs can further incite conflict among health care team members, families, and patients. Pediatric patient care has a higher potential for con...

journal_title：Anesthesia and analgesia

authors： Sinskey JL,Chang JM,Shibata GS,Infosino AJ,Rouine-Rapp K

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Capsaicin, the active component of chili peppers, can produce sensory-selective peripheral nerve blockade. Coadministration of capsaicin and tetrodotoxin, a site-1 sodium channel blocker, can achieve a synergistic effect on duration of nerve blocks. However, capsaicin can be neurotoxic, and tetrodotoxin can ...

journal_title：Anesthesia and analgesia

authors： Shomorony A,Santamaria CM,Zhao C,Rwei AY,Mehta M,Zurakowski D,Kohane DS

更新日期：2019-09-01 00:00:00

abstract：:Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a st...

journal_title：Anesthesia and analgesia

authors： Katz D,Hamburger J,Batt D,Zahn J,Beilin Y

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Bilateral paravertebral block (PVB) is a suitable alternative to thoracic epidural analgesia (TEA) for abdominal surgeries. This randomized clinical trial aims to determine if PVB is noninferior to TEA in terms of analgesia after midline laparotomy. METHODS:Seventy American Society of Anesthesiologists (ASA...

journal_title：Anesthesia and analgesia

authors： Sondekoppam RV,Uppal V,Brookes J,Ganapathy S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Risk of intraoperative hypothermia is relatively high in middle-aged and elderly patients undergoing curative resection of esophageal cancer, which may cause myocardial ischemia during the early postoperative period. The objective of this study was to compare aggressive or standard body temperature managemen...

journal_title：Anesthesia and analgesia

authors： Zhang Z,Xu M,Wu D,Zhang X,Wu J

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:We implemented a previously described barcode-based drug safety system in all of our anesthetizing locations. Providers were instructed to scan the barcode on syringes using our Anesthesia Information Management System before drug administration, but the rate of provider adherence was low. We studied an impl...

journal_title：Anesthesia and analgesia

authors： Bowdle TA,Jelacic S,Nair B,Zucker F,Bussey LS,Togashi K,Yang JT,Lang J

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Pulse oximetry-derived oxygen saturation is typically >97% in normoxia and hyperoxia, limiting its clinical use. The new Oxygen Reserve Index (ORi), a relative indicator of the partial pressure of oxygen dissolved in arterial blood (PaO2) in the range of 100-200 mm Hg, may allow additional monitoring of oxyg...

journal_title：Anesthesia and analgesia

authors： Vos JJ,Willems CH,van Amsterdam K,van den Berg JP,Spanjersberg R,Struys MMRF,Scheeren TWL

更新日期：2019-08-01 00:00:00

abstract：:Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic in the United States. However, efforts to study and address the issue have been stymied by the lack of a standard definition, which has also hampered efforts to measure the incidence of and risk factors for persistent postopera...

journal_title：Anesthesia and analgesia

authors： Kent ML,Hurley RW,Oderda GM,Gordon DB,Sun E,Mythen M,Miller TE,Shaw AD,Gan TJ,Thacker JKM,McEvoy MD,POQI-4 Working Group.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, a selective α2-adrenergic agonist currently approved for continuous intensive care unit sedation, is being widely evaluated for its role as a potential anesthetic. The closed-loop anesthesia delivery system (CLADS) is a method to automatically administer propofol total intravenous anesthesia...

journal_title：Anesthesia and analgesia

authors： Dutta A,Sethi N,Sood J,Panday BC,Gupta M,Choudhary P,Puri GD

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:In vivo animal assays are a cornerstone of preclinical pain research. An optimal stimulus for determining the activity of potential analgesics would produce responses of a consistent magnitude on repeated testing. Intraplantar (i.pl.) injection of hypertonic saline (HS) in mice produces robust nociceptive re...

journal_title：Anesthesia and analgesia

authors： Asiri YI,Fung T,Schwarz SKW,Barr AM,Puil E,MacLeod BA

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial su...

journal_title：Anesthesia and analgesia

authors： Godai K,Takahashi K,Kashiwagi Y,Liu CH,Yi H,Liu S,Dong C,Lubarsky DA,Hao S

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Insufficient fixation of an epidural catheter may result in migration of the catheter and eventual catheter failure. However, the best fixation method remains to be established. Aron Alpha A (2-ethyl cyanoacrylate) adhesive is approved for clinical use and can be used for surgical adhesion to both skin and b...

journal_title：Anesthesia and analgesia

authors： Tadokoro T,Kakinohana M,Navarro M,Goya M,Odo Y

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The switch from International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) for coding of inpatient procedures in the United States increased the number of procedural codes more than 19-fold,...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,O'Neill L

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Pilot studies applying point-of-care ultrasound (POCUS) in preeclampsia indicate the presence of pulmonary interstitial edema, cerebral edema, and cardiac dysfunction. Laboratory markers of oncotic pressure (albumin) and cardiac dysfunction (brain natriuretic peptide [BNP]) may be abnormal, but the clinical ...

journal_title：Anesthesia and analgesia

authors： Ortner CM,Krishnamoorthy V,Neethling E,Flint M,Swanevelder JL,Lombard C,Fawcus S,Dyer RA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Frailty, a state of decreased physiological reserve, is strongly associated with perioperative mortality in older adults. However, the mechanism by which frailty is associated with mortality is not yet understood. Autonomic dysfunction in the form of decreased intraoperative hemodynamic variability has been ...

journal_title：Anesthesia and analgesia

authors： James LA,Levin MA,Lin HM,Deiner SG

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Perioperative major adverse cardiovascular and cerebrovascular events (MACCEs) are incompletely understood, and risk prediction is imprecise. Atherogenic leukocytes are crucial in cardiovascular events. However, it is unclear if surgical interventions affect leukocyte counts or activation status. Therefore, ...

journal_title：Anesthesia and analgesia

authors： Handke J,Scholz AS,Gillmann HJ,Janssen H,Dehne S,Arens C,Kummer L,Uhle F,Weigand MA,Motsch J,Larmann J

更新日期：2019-06-01 00:00:00